EPJE Topical Issue : Physical modeling and experimental studies of cancer progression

Details

Published on 27 August 2024

Guest Editors: Corey O’Hern and Stefano Villa

Submissions are invited for a Topical Issue of EPJ E on Physical modeling and experimental studies of cancer progression.

A physical understanding of the progression of cancer, including cancer growth and metastasis, will greatly aid in the development of therapeutic treatments. Tumor growth creates large pressures on surrounding tissue and stroma, which can further stimulate tumor proliferation. During cancer metastasis, cancer cells migrate away from the primary tumor and form secondary tumor sites in other organs, which leads to much higher mortality rates for cancer patients. Previous experimental studies of many cancer types have revealed that mechanical forces play a crucial role in both cancer growth and metastasis. For example, pressure built up during tumor growth alters cell gene expression, cancer cell proliferation, and blood flow. Cancer cells can also readily change their shapes and have a heightened migratory response that facilitates tumor invasion and metastasis. This special issue seeks contributions from researchers who carry out experimental, theoretical, and computational studies to understand the physical mechanisms that promote tumor growth and give rise to cancer metastasis. We also welcome articles that seek to identify features of the tumor microenvironment, as well as physical properties of tumor cells that promote or inhibit cancer cell migration, growth, and metastasis.

Original research papers, Reviews, and Colloquium-type articles focusing on the latest experimental, theoretical or computational advancements in the field as described above are welcome. We invite contributors to communicate their intention to submit manuscripts for this Topical Issue to the Guest Editors as soon as possible. Please provide the tentative title of the paper and a short abstract. The full manuscripts should be submitted before the deadline directly to the EPJ E Editorial Office at https://www.editorialmanager.com/epje/.

Submissions should be clearly identified as intended for the Topical Issue on ‘Physical modeling and experimental studies of cancer progression’. Papers will be published continuously and will appear as soon as accepted on the journal website. The electronic version of the Topical Issue will contain all accepted papers in the order of publication. All submitted papers will be refereed according to the usual high standards of the journal. More information about EPJ E, including instructions for authors is available here.

Guest Editors of the Topical Issue

Corey O’Hern
Yale University, New Haven, CT, United States of America

Stefano Villa
Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany

Open Access

EPJ E is a hybrid journal offering Open Access publication. If the CORRESPONDING author is affiliated to an institute that has an Open Access agreement with Springer, the OA publication - if verified - is paid by the agreement partner. All OA agreements are listed with more details Here.. Eligibility will be automatically verified when the corresponding author is requested to complete the relevant affiliation information after acceptance of the paper during the production process. Corresponding authors not affiliated to institutes with Open Access Agreements are redirected to proceed with “Please select your publishing model” and have to decide between paying the current Open Access fee - for details see How to publish with us | The European Physical Journal Special Topics (springer.com) and Open Choice programme) - or choosing the subscription option without any publication charges.